Osteology – II Osteology – II These advanced questions cover detailed aspects of bone biology, genetics, and physiology, providing a deeper understanding of osteology. 1 / 10 Which cytokine, produced by osteoblasts, is essential for the differentiation and activation of osteoclasts and is often targeted in treatments for osteoporosis? IL-6 TNF-α RANKL IL-1β RANKL (Receptor Activator of Nuclear factor Kappa-Β Ligand) RANKL (Receptor Activator of Nuclear factor Kappa-Β Ligand) 2 / 10 Osteoarthritis is primarily characterized by the degradation of which type of cartilage found in synovial joints? Fibrocartilage Elastic cartilage Hyaline cartilage Articular cartilage 3 / 10 Which of the following growth factors is most critical in the initial stages of fracture healing and stimulates the recruitment and proliferation of mesenchymal stem cells? Transforming growth factor-beta (TGF-β) Bone morphogenetic protein (BMP) Insulin-like growth factor (IGF) Vascular endothelial growth factor (VEGF) 4 / 10 What is the primary mineral component of bone, providing it with its hardness and strength? Calcium phosphate Hydroxyapatite Calcium carbonate Magnesium sulfate 5 / 10 Which hormone, produced by the thyroid gland, lowers blood calcium levels by inhibiting osteoclast activity and stimulating calcium excretion by the kidneys? Calcitonin Parathyroid hormone (PTH) Vitamin D Aldosterone 6 / 10 Which protein, produced by osteoblasts, binds to RANKL and inhibits osteoclastogenesis, thereby reducing bone resorption? Osteoprotegerin (OPG) Sclerostin Matrix Gla protein (MGP) Fibroblast growth factor 23 (FGF23) 7 / 10 During endochondral ossification, which zone of the growth plate is characterized by the proliferation of chondrocytes and increased cell division? Resting zone Proliferation zone Hypertrophic zone Calcification zone 8 / 10 The condition characterized by the excessive breakdown and formation of bone tissue, leading to bone pain, deformities, and fractures, is known as: Osteomalacia Paget’s disease Osteomyelitis Rickets 9 / 10 The process by which bone adapts to mechanical loading, often described by Wolff’s law, involves which type of bone cell? Osteoblasts Osteoclasts Osteocytes Chondrocytes 10 / 10 Mutations in the gene coding for the protein “collagen type I” are most commonly associated with which genetic bone disorder? Osteopetrosis Osteogenesis imperfecta Paget’s disease Fibrous dysplasia Your score isThe average score is 0% 0% Restart quiz By WordPress Quiz plugin